GO:0035976 cellular_component transcription factor AP-1 complex
| PAG Title | GO:0035976 cellular_component transcription factor AP-1 complex |
| PAG ID | TAX023180 |
| Type | A |
| Source Link |  GOA |
| Publication Reference | NA |
| PAG Description | A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes. |
| Species | Homo sapiens |
| nCoCo Score | 1,217 |
| Base PAG ID | TAX023180 |
| Human Phenotyte Annotation | |
| Curator | PAGER curation team |
| Curator Contact | PAGER-contact@googlegroups.com |
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